Throughout different stages of drug development & bioprocessing there is a need for accurate quantification of antibodies. Antibody titre is a crucial indicator of the quality of a clone during cell line development or of the suitability of production parameters during process development.
Samples are often present in crude form, meaning the antibodies are suspended in a solution containing a multitude of other proteins and biomolecules. Traditional methods of quantification require sample purification, which is a time-consuming and often expensive process.
Amperia performs antibody quantification directly from crude samples, without the need for pre-processing. Protein A Red-Sensors are ideal for quantification of a range of non-human & human antibodies. Measurement takes as little as 1 minute per sample. Amperia allows for walk-away automation, freeing up valuable time, while reducing error related to manual handling. See how Amperia is used to quantify antibodies or test it yourself!
At-line physical titer assays in AAV bioprocessing offer several benefits. They enable real-time monitoring of vector concentration during production, facilitating timely adjustments to optimize yield and quality. This approach reduces processing time and resource consumption by providing rapid feedback on vector titers. Additionally, at-line assays streamline workflow by minimizing the need for off-line sample analysis, thus enhancing process efficiency. Ultimately, these benefits contribute to faster development timelines, improved scalability, and cost-effectiveness in AAV bioprocessing.
Using RED analysis, Amperia can be placed at line to provide these analytics in a fully automated fashion. No need to send samples away to another analytical lab or perform time consuming manual processes. Simply place your samples into a well plate and Amperia will give you fast and accurate titer data.
ELISA (Enzyme-Linked Immunosorbent Assay) plays a crucial role in drug development by enabling the detection and quantification of target molecules, such as proteins or antibodies. It provides a sensitive and specific method for measuring biomarkers, evaluating drug efficacy, and monitoring drug-target interactions.
Despite the adoption of automated systems for high-throughput applications, manual ELISA is still common due to its flexibility and ease of setup. However, it is a time-consuming process that requires multiple steps, which can be prone to human error and variability, resulting in reduced reproducibility, increased assay variability, and potential data inconsistencies.
Amperia is a highly versatile system that can automate the entire ELISA workflow. It is an all-in-one system, with a compact footprint suited for any laboratory. With its customizable platform, Amperia allows researchers to automate ELISA assays tailored to their specific needs, enhancing accuracy, reproducibility, and throughput. By eliminating manual handling, Amperia minimizes human errors, reduces assay variability, and ensures consistent and reliable results, thus accelerating drug development and biomedical research. In addition, Amperia’s measurement method allows for protocols not possible with traditional ELISA, such as experiments with incubation times of under a minute, repeated measurement of the same sample or tracking of dissociation. See how Amperia is used to streamline ELISA workflows or test it yourself!
At Abselion, we value your insights and ideas. We believe that collaboration is the key to unlocking new possibilities and driving advancements in biotechnology. We are constantly striving to innovate and push the boundaries of biotechnology with our cutting-edge product, to meet the diverse needs of our customers.
We believe that the best ideas often come from those who use our products, and that's why we invite you, our valued customers, to join us in shaping the future of Biotechnology. Share your visionary ideas for new application areas of Amperia. Is there a specific challenge you're facing that could benefit from our technology? Are there unexplored domains where we can help you to make a significant impact? We want to hear from you!
Let's pioneer the next generation of breakthroughs in biotechnology. Share your ideas with us today, and let's shape the future of Abselion together!
Quantify antibodies from crude samples using an affordable platform that can easily be placed at line. Measurements take as little as 1 minute per sample. Optimize the assessment of your transient expression, accelerate your cell line development programme, or gain access to at line titer readings right next to your bioreactor.
Compact size means Amperia can be operated anywhere, whether it is within a laminar flow cabinet or on a tight lab bench.
Quantifying the physical titer of viral vectors in bioprocessing is crucial for maintaining consistency, efficacy, and safety of products such as gene therapies and vaccines. Accurate measurement ensures uniformity between batches, optimizes resource utilization, and aids in regulatory compliance, streamlining the development and approval process.
Amperia allows users to automate capsid ELISAs and capture physical titer, at-line in real time. This relieves analytical bottlenecks that can be caused by the need for central analytical support.
Automate your assays with minimal setup time. Amperia is fully compatible with standard ELISA assays and reagents. Transfer existing assays to reduce manual labour or accelerate the development of new assays.
Amperia’s measurement method allows for protocols not possible with traditional ELISA. Run experiments with incubation times of under a minute, repeated measurement of the same sample or track dissociation of molecules.
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