Throughout different stages of drug development there is a need for accurate quantification of antibodies. Antibody titre is a crucial indicator of the quality of a clone during cell line development or of the suitability of production parameters during process development.
Samples are often present in crude form, meaning the antibodies are suspended in a solution containing a multitude of other proteins and biomolecules. Traditional methods of quantification require sample purification, which is a time-consuming and often expensive process.
Amperia performs antibody quantification directly from crude samples, without the need for pre-processing. Protein A Red-Sensors are ideal for quantification of a range of non-human & human antibodies. Measurement takes as little as 30 min for 30 samples. Amperia allows for walk-away automation, freeing up valuable time, while reducing error related to manual handling. See how Amperia is used to quantify antibodies or test it yourself!
In collaboration with PetMedixRead application note
In collaboration with AgenusRead application note
ELISA (Enzyme-Linked Immunosorbent Assay) plays a crucial role in drug development by enabling the detection and quantification of target molecules, such as proteins or antibodies. It provides a sensitive and specific method for measuring biomarkers, evaluating drug efficacy, and monitoring drug-target interactions.
Despite the adoption of automated systems for high-throughput applications, manual ELISA is still common due to its flexibility and ease of setup. However, it is a time-consuming process that requires multiple steps, which can be prone to human error and variability, resulting in reduced reproducibility, increased assay variability, and potential data inconsistencies.
Amperia is a highly versatile system that can automate the entire ELISA workflow. It is an all-in-one system, with a compact footprint suited for any laboratory. With its customizable platform, Amperia allows researchers to automate ELISA assays tailored to their specific needs, enhancing accuracy, reproducibility, and throughput. By eliminating manual handling, Amperia minimizes human errors, reduces assay variability, and ensures consistent and reliable results, thus accelerating drug development and biomedical research. In addition, Amperia’s measurement method allows for protocols not possible with traditional ELISA, such as experiments with incubation times of under a minute, repeated measurement of the same sample or tracking of dissociation. See how Amperia is used to streamline ELISA workflows or test it yourself!
In collaboration with NanoSyrinxRead application note
Accurate identification of reagents, such as antibodies, enzymes, and substrates, is crucial for maintaining assay consistency, reproducibility, and traceability. In biopharmaceutical manufacturing, proper reagent identification guarantees the production of consistent and high-quality therapeutics and is often part of the official regulation.
Identification of biologics poses several challenges due to their complexity and variability. Proteins exhibit diverse characteristics, arising from production methods or clones. Identification and characterization requires comprehensive analysis, often involving assessment of binding assays between specific binding partners.
Amperia can help improve reagent identification by accelerating and standardizing the process. Compact footprint, ease of use and low maintenance make it an ideal choice for application outside of laboratories or operation by non-technical staff. Amperia runs fully automated binding assays, thereby ensuring consistency and minimizing human error. See how Amperia can be used for reagent validation or test it yourself!
In collaboration with Fresenius-KabiRead application note
At Abselion, we value your insights and ideas. We believe that collaboration is the key to unlocking new possibilities and driving advancements in biotechnology. We are constantly striving to innovate and push the boundaries of biotechnology with our cutting-edge product, to meet the diverse needs of our customers.
We believe that the best ideas often come from those who use our products, and that's why we invite you, our valued customers, to join us in shaping the future of Biotechnology. Share your visionary ideas for new application areas of Amperia. Is there a specific challenge you're facing that could benefit from our technology? Are there unexplored domains where we can help you to make a significant impact? We want to hear from you!
Let's pioneer the next generation of breakthroughs in biotechnology. Share your ideas with us today, and let's shape the future of Abselion together!